Xenoduplex Analysis—A Method for Comparative Gene Mapping Using Hybrid Panels

Xenoduplex analysis--a method for comparative gene mapping using hybrid panels.

Somatic cell hybrid (SCH) panels and radiation hybrid (RH) panels are powerful resources for comparative gene mapping because gene assignments are made without the detection of genetic polymorphism as needed for linkage mapping. A frequently encountered problem, however, is that the gene specific primers may amplify homologous PCR products of equal length from the donor and recipient species of...

hybrid method for prediction of metastasis in breast cancer patients using gene expression signals

background: using primary tumor gene expression has been shown to have the ability of finding metastasis-driving gene markers for the prediction of breast cancer recurrence (bcr). however, there are some difficulties associated with the analysis of microarray data which led to poor predictive power and inconsistency of the previously introduced gene signatures. methods: in this study a hybrid m...

Study on Design Method of Joint Panels for Hybrid Railway Rigid-frame Bridges

A Classification Method for E-mail Spam Using a Hybrid Approach for Feature Selection Optimization

Spam is an unwanted email that is harmful to communications around the world. Spam leads to a growing problem in a personal email, so it would be essential to detect it. Machine learning is very useful to solve this problem as it shows good results in order to learn all the requisite patterns for classification due to its adaptive existence. Nonetheless, in spam detection, there are a large num...

A Hybrid GMM and Codebook Mapping Method for Spectral Conversion

This paper proposes a new mapping method combining GMM and codebook mapping methods to transform spectral envelope for voice conversion system. After analyzing overly smoothing problem of GMM mapping method in detail, we propose to convert the basic spectral envelope by GMM method and convert envelope-subtracted spectral details by GMM and phone-tied codebook mapping method. Objective evaluatio...